Cedars-Sinai Biomanufacturing Center

Cedars Sinai Biomanufacturing Center

Cedars-Sinai Biomanufacturing Center

Co-Locating R&D and Production

The Cedars-Sinai Biomanufacturing Center was created to advance research and application for the conversion of custom-designed stem cells into individualized therapies for some of the world’s more insidious diseases. Graduating from Cedars-Sinai’s laboratories for basic research, the new center is highly customized to focus on process development and commercial production of their technologies. To meet the client’s needs, we provided tenant improvement services at Cedars’ Pacific Design Center, located blocks away from the Cedars-Sinai Medical Center campus in Los Angeles. The mission of the design team was to create a space inspired by the pedigree of the iconic Pacific Design Center yet technically sophisticated to meet the rigors of advanced research and production.

Abundant Flexible Workspace

The new facility features research and development laboratories, office space and cGMP (Current Good Manufacturing Practice) production space to support Phase I and II clinical trials complying with Food and Drug Administration regulations. The cGMP space consists of a series of controlled, classified cleanrooms with ISO Classes 6, 7 and 8, providing a total of seven rooms dedicated for cell production lines plus specialized process rooms.

Controlled unclassified spaces include quality control laboratories, material storage and mechanical support rooms. The product development laboratories are also un-classified clean spaces intended to have a ‘GMP-lite’ operation for the production of non-clinical/research grade cell products.

To handle both classified and un-classified areas, the building’s mechanical systems are segregated for better control and adherence to guidelines, as well as for energy economy. The cleanroom ventilation system was also designed to be able to isolate each cell processing room from the rest to provide flexibility to clean or replace equipment while other spaces remain operational.

Cedars Sinai Biomanufacturing Center
Client
Cedars-Sinai Medical Center
Location

West Hollywood, CA
United States

Size
23,300 sf (2,164 m²)